Illness and Diseases

In vitro study on human cytomegalovirus affecting early pregnancy villous EVT’s invasion function. Discussion

Discussion HCMV is the most common pathogen in intrauterine infection. Among the new born babies in Europe and America, HCMV infection rate is 2%, while that in developing countries is even higher. HCMV intrauterine infection may cause miscarriage, stillbirth, fetus developmental retardation, central nervous system damage and other serious results, but its specific pathogenesis remains […]

April 13, 2011 – 10:58 pm | By Dan Frost | Posted in Diseases | Comments (0)

In vitro study on human cytomegalovirus affecting early pregnancy villous EVT’s invasion function. Results

Controls The above immunohistochemical procedures controls were performed replacing the primary antibody by PBS. Further controls were performed omitting the secondary antibody. The controls were always negative. Mexican online pharmacies Western Blot detection It is to detect c-erbB-2, MMP-2 and MMP-9 expression levels. Referring to the instruction of kits, two groups of villous total protein […]

April 9, 2011 – 5:09 pm | By Dan Frost | Posted in Diseases | Comments (0)

In vitro study on human cytomegalovirus affecting early pregnancy villous EVT’s invasion function. Materials

Specimen and sources of the virus The tissue of villus is from healthy pregnant women whose peripheral blood is HCMV antibody negative and whose gestational age are between 5 to 10 weeks, who are voluntarily conducted abortion because of planned parenthood, from department of gynecology and obstetrics of Tongji Hospital of Tongji Medical College of […]

April 7, 2011 – 10:57 pm | By Dan Frost | Posted in Diseases | Comments (0)

In vitro study on human cytomegalovirus affecting early pregnancy villous EVT’s invasion function

Background Human cytomegalovirus (HCMV) is the most common pathogen in uterus during pregnancy, which may lead to some serious results such as miscarriage, stillbirth, cerebellar malformation, fetus developmental retardation, but its pathogenesis has not been fully explained. The hypofunction of extravillous cytotrophoblast (EVT) invasion is the essential pathologic base of some complications of pregnancy. c-erbB-2 […]

April 5, 2011 – 10:41 pm | By Dan Frost | Posted in Diseases | Comments (0)

DEFINITIONS OF DISEASE, ILLNESS, AND SICKNESS

As Nordenfelt in particular criticizes the definitions of the concepts disease, illness, and sickness presented by Andrew Twaddle (Twaddle, 1994a, 1973, 1979), I will take these definitions as a point of departure and cite them at some length. According to Twaddle, disease is defined in the following way: ‘‘Disease is a health problem that consists […]

April 1, 2011 – 6:06 pm | By Dan Frost | Posted in Diseases | Comments (0)

Viagra Canadian Pharmacy: On the Triad Disease, Illness and Sickness

ABSTRACT The point of departure for this article is a review of the discussion between Twaddle and Nordenfelt on the concepts of disease, illness, and sickness, and the objective is to investigate the fruitfulness of these concepts. It is argued that disease, illness, and sickness represent different perspectives on human ailment and that they can […]

March 31, 2011 – 3:44 pm | By Dan Frost | Posted in Diseases | Tagged Canadian pharmacy, viagra online canada | Comments (0)

Mechanism of Hepcidin Action

Hepcidin derived from extrahepatic sources may also exert control over local iron fluxes within tissues in which hepcidin is produced. For example, the central nervous system is separated from the plasma by the blood-brain barrier, and circulating hepcidin may not be transported across this barrier. However, brain tissue itself was reported to express hepcidin, allowing […]

March 26, 2011 – 4:55 pm | By Dan Frost | Posted in Other | Comments (0)

The Role of Hepcidin in Iron Metabolism. Part 2

Structurally, the hepcidin peptide resembles a bent hairpin held together by four disulfide bonds. The disulfide connectivity was recently revised. NMR spectroscopy, partial reductive alkylation and Fourier transform mass spectroscopy were used to resolve ambiguities arising from the proximity of the four disulfides. The new model indicates that two bonds stabilize the antiparallel β-sheet, and […]

March 25, 2011 – 5:23 pm | By Dan Frost | Posted in Other | Comments (0)

The Role of Hepcidin in Iron Metabolism

Hepcidin is the central regulator of systemic iron homeostasis. Dysregulation of hepcidin production results in a variety of iron disorders. Hepcidin deficiency is the cause of iron overload in hereditary hemochromatosis, iron-loading anemias, and hepatitis C. Hepcidin excess is associated with anemia of inflammation, chronic kidney disease and iron-refractory iron deficiency anemia. Diagnostic and therapeutic […]

March 23, 2011 – 6:26 pm | By Dan Frost | Posted in Other | Comments (0)

Viral Phenotype and Immune Response in Primary Human Immunodeficiency Virus Type 1 Infection. Part 5

The emergence of SI T cell-line tropic variants in longterm infected individuals progressing to AIDS is well established. This overt replication of SI clones is thought to be due to an increasing qualitative immune deficiency with ongoing infection. Remarkably, in the three individuals with SI isolates described here, these isolates could be detected from the […]

March 20, 2011 – 2:45 pm | By Dan Frost | Posted in Infections | Comments (0)